Posts PICO Table March 15, 2026 / AssignmentTopic/QuestionPICO 1For pts 55+ yo w/ a hx of htn, does intensive BP control (SBP ≤120-140) reduce incidence of MACE compared to standard BP control (SBP 140-160)?PICO 2For patients with resistant hypertension, how does universal vs. targeted primary aldosteronism (PA) screening affect MACE and all-cause mortality?PICO 3In woman w/ recurrent UTIs (≥2 in 6 months or 3≥ in 12 months), do nonantibiotic prophylactic strategies reduce theincidence of symptomatic, culture-verified UTIs compared to placebo?PICO 4In patients with non-valvular atrial fibrillation (AFib), do left-atrial appendage occlusion (LAAO) devices (ex Watchman) compared with long-term anticoagulation (AC) result in worse clinical outcomes, including morbidity and stroke?PICO 5In hospitalized adults, do EMR-based AKI alerts, compared to standard laboratory reporting, improve clinical outcomes such as mortality and morbidity?PICO 6In adults with new pleural effusion, does thoracentesis with pleural fluid analysis, compared to other testing modalities,improve the diagnostic accuracy for malignancy?Mini-CAT FinalIn adults with prediabetes or type 2 diabetes, does intermittent fasting compared to continuous calorie restriction improve glycemic control as measured by HbA1c and fasting glucose?
